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Anti-AP2S1 Antibody CAB9263
Key Features

AP2S1 Rabbit Monoclonal Antibody (CAB9263)

Datasheet MSDS
SKU CAB9263
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rabbit
Synonyms AP17, FBH3, HHC3, FBHOk, CLAPS2, AP2S1
Research Use Cell Biology
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

AP2S1 Monoclonal Antibody (CAB9263)

The AP2S1 Monoclonal Antibody (CAB9263) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, raised in rabbits, is specifically reactive with human samples and is validated for use in various applications, including Western blot and immunofluorescence.AP2S1 is a subunit of the AP2 adaptor protein complex, which plays a crucial role in the internalization of cell surface receptors and other membrane proteins. Dysregulation of this pathway has been linked to various diseases, including cancer and neurological disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.

Product Name:AP2S1 Monoclonal Antibody
SKU:CAB9263
Size:20μL, 100μL
Reactivity:Mouse
Clone Number:ARC1500
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MIRF ILIQ NRAG KTRL AKWY MQFD DDEK QKLI EEVH AVVT VRDA KHTN FVEF RNFK IIYR RYAG LYFC ICVD VNDN NLAY LEAI HNFV EVLN EYFH NVCE
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AP17, FBH3, HHC3, FBHOk, CLAPS2, AP2S1
Positive Sample:Mouse brain
Cellular Localization:Clathrin-Coated Endocytic Vesicle, Cytoplasmic Side Of Plasma Membrane, Cytosol, Plasma Membrane, Postsynapse, Presynapse.
Calculated MW:17kDa
Observed MW:17kDa

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID1175
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Mouse brain , using AP2S1 Rabbit mAb (CAB9263) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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