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Anti-ATF5 Antibody (CAB3563)

SKU:
CAB3563
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATFX
HMFN0395
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

Product Name:ATF5 Rabbit mAb
Product Code:CAB3563
Size:20uL, 50uL, 100uL
Synonyms:ATFX, HMFN0395
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ATF5
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, Jurkat, SH-SY5Y, Mouse liver, Mouse brain, Rat lung, Rat liver, Rat brain
Immunogen:A synthesized peptide derived from human ATF5
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:22809
Uniprot:Q9Y2D1
Calculated MW:31kDa
Observed MW:35kDa
UniProt Protein Function:ATF-5: Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Belongs to the bZIP family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: centrosome; cytoplasm; nucleoplasm; nucleus

Molecular Function:chromatin binding; kinase binding; protein binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity; tubulin binding

Biological Process: fat cell differentiation; granule cell precursor proliferation; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of centrosome cycle; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent

UniProt Code:Q9Y2D1
NCBI GenInfo Identifier:308153647
NCBI Gene ID:22809
NCBI Accession:Q9Y2D1.4
UniProt Secondary Accession:Q9Y2D1,Q9BSA1, Q9UNQ3, B3KND3,
UniProt Related Accession:Q9Y2D1
Molecular Weight:30,674 Da
NCBI Full Name:Cyclic AMP-dependent transcription factor ATF-5
NCBI Synonym Full Names:activating transcription factor 5
NCBI Official Symbol:ATF5  
NCBI Official Synonym Symbols:ATFX; HMFN0395  
NCBI Protein Information:cyclic AMP-dependent transcription factor ATF-5
UniProt Protein Name:Cyclic AMP-dependent transcription factor ATF-5
UniProt Synonym Protein Names:Activating transcription factor 5; Transcription factor ATFx
Protein Family:Cyclic AMP-dependent transcription factor
UniProt Gene Name:ATF5  
UniProt Entry Name:ATF5_HUMAN

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