The Anti-CBX2 Antibody (CAB3294) is a valuable tool for researchers studying the role of CBX2 in various cellular processes. CBX2 is a chromobox protein that is involved in gene regulation and plays a critical role in maintaining chromatin structure. The antibody, raised in rabbits, is highly specific for CBX2 and is validated for use in various applications, including Western blot, immunohistochemistry, and immunofluorescence.CBX2 is known to be involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of CBX2 has been linked to the development of certain cancers, making it a potential therapeutic target for cancer treatment.
By using the Anti-CBX2 Antibody, researchers can study the expression and localization of CBX2 in different cell types and tissues, providing valuable insights into its role in normal physiology and disease states.Overall, the Anti-CBX2 Antibody (CAB3294) is a reliable tool for researchers interested in studying the function of CBX2 and its implications in various biological processes, including cancer development and progression. Its specificity and versatility make it a valuable asset for research in molecular biology, oncology, and cell biology.
Product Name:
CBX2 Rabbit Monoclonal Antibody
SKU:
CAB3294
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 433-532 of human CBX2 (Q14781).
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
84733
Clone Number:
ARC1939
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CBX2 Rabbit mAb (CAB3294) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
