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CPSF73 Rabbit Monoclonal Antibody (CAB2222)

SKU:
CAB2222
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CPSF3
CPSF-73
CPSF73
cleavage and polyadenylation specific factor 3
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CPSF73 Rabbit Monoclonal Antibody
SKU:CAB2222
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 585-684 of human CPSF3 (Q9UKF6).
Sequence:LEVQ SNPK IRKG AVQK VSKK LEMH VYSK RLEI MLQD IFGE DCVS VKDD SILS VTVD GKTA NLNL ETRT VECE EGSE DDES LREM VELA AQRL YEAL TPVH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CPSF73; NEDMHS; CPSF-73; NEDMHSN
Positive Sample:HeLa,293T,SH-SY5Y,Mouse liver,Mouse kidney,Mouse uterus,Rat spleen
Conjugate:Unmodified
Cellular Localization:Nucleus
Calculated MW:77kDa
Observed MW:75kDa

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.

Purification Method:Affinity purification
Gene ID:51692
Clone Number:ARC2567
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using CPSF73 antibody (CAB2222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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