null

Anti-PD-L1 antibody (HDAB0112)

SKU:
HDAB0112
Product Type:
Antibody
Reactivity:
Human
Application:
ELISA
Application:
Flow Cytometry
Isotype:
Rabbit IgG
Antibody Type:
Monoclonal
€749
Frequently bought together:

Description

Product Name:Anti-PD-L1 antibody (HDAB0112)
Product Code:HDAB0112
Size:100 µg
Application:ELISA,Flow Cyt
Reactivity:Human
Host:Rabbit
Synonyms:PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Description:This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Antigen:PD-L1
Type:Primary
Immunogen:Recombinant human PD-L1 (Phe19-Arg328) (PME100480) produced by using human HEK293 cells
Clonality:Monoclonal
Clone:DM123
Isotype:Rabbit IgG
Gene ID:29126
Swiss-Prot:Q9NZQ7
Molecular Weight:26 kDa
Shipping:Blue Ice
Purification:Purified from cell culture supernatant by affinity chromatography
Format:Lyophilized
Storage:Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Preservative:0.1% Procline 300
Reconstitution:Reconstitute with deionized water
Application Advice:ELISA 1/5000-10000, Flow Cyt  1/100

Related Products