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PGD Rabbit Monoclonal Antibody (CAB0563)

SKU:
CAB0563
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PGD
6PGD
phosphogluconate dehydrogenase
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PGD Rabbit Monoclonal Antibody
SKU:CAB0563
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 384-483 of human PGD (P52209).
Sequence:PELQ NLLL DDFF KSAV ENCQ DSWR RAVS TGVQ AGIP MPCF TTAL SFYD GYRH EMLP ASLI QAQR DYFG AHTY ELLA KPGQ FIHT NWTG HGGT VSSS SYNA
Tested Applications:WB IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:6PGD; PGD
Positive Sample:HeLa,HepG2,Jurkat,Mouse lung,Mouse liver,Mouse spleen,Rat lung,Rat liver,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Cytoplasm
Calculated MW:53kDa
Observed MW:49kDa

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:5226
Clone Number:ARC2516
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PGD Rabbit mAb (CAB0563) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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