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Anti-PLC beta 3 (PLCB3) Antibody (CAB19738)

SKU:
CAB19738
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

Product Name:PLC beta 3 (PLCB3) Rabbit mAb
Product Code:CAB19738
Size:20uL, 50uL, 100uL
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human PLC beta 3 (PLC beta 3 (PLCB3))
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HeLa, OVCAR3
Immunogen:A synthesized peptide derived from human PLC beta 3 (PLC beta 3 (PLCB3))
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5331
Uniprot:Q01970
Calculated MW:150kDa
Observed MW:150KDa
UniProt Protein Function:PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate.
UniProt Protein Details:

Protein type:Phospholipase; EC 3.1.4.11; Carbohydrate Metabolism - inositol phosphate

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytosol; nucleoplasm; protein complex; sarcolemma

Molecular Function:calcium ion binding; calmodulin binding; phosphoinositide phospholipase C activity; phospholipase C activity; signal transducer activity

Biological Process: G-protein coupled receptor protein signaling pathway; inositol phosphate metabolic process; lipid catabolic process; post-Golgi vesicle-mediated transport; regulation of systemic arterial blood pressure; synaptic transmission

NCBI Summary:This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
UniProt Code:Q01970
NCBI GenInfo Identifier:1730573
NCBI Gene ID:5331
NCBI Accession:Q01970.2
UniProt Secondary Accession:Q01970,Q8N1A4, A5PKZ6, G5E960,
UniProt Related Accession:Q01970
Molecular Weight:131,205 Da
NCBI Full Name:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
NCBI Synonym Full Names:phospholipase C beta 3
NCBI Official Symbol:PLCB3  
NCBI Protein Information:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Protein Name:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Synonym Protein Names:Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
Protein Family:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
UniProt Gene Name:PLCB3  
UniProt Entry Name:PLCB3_HUMAN

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