null

Anti-RPL7A Antibody (CAB19247)

SKU:
CAB19247
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RPL7A
L7A
SURF3
TRUP
ribosomal protein L7a
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

Product Name:RPL7A Rabbit mAb
Product Code:CAB19247
Size:20uL, 50uL, 100uL
Synonyms:RPL7A, L7A, SURF3, TRUP, ribosomal protein L7a
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RPL7A.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein of human RPL7A.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6130
Uniprot:P62424
Calculated MW:30kDa
Observed MW:Refer to figures
UniProt Protein Function:RPL7A: Belongs to the ribosomal protein L7Ae family.
UniProt Protein Details:

Protein type:Nuclear receptor co-regulator; Translation; Ribosomal

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleolus; nucleus; polysomal ribosome

Molecular Function:protein binding; RNA binding

Biological Process: maturation of LSU-rRNA; mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription

NCBI Summary:Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P62424
NCBI GenInfo Identifier:54039239
NCBI Gene ID:6130
NCBI Accession:P62424.2
UniProt Secondary Accession:P62424,P11518, Q5T8U4,
UniProt Related Accession:P62424
Molecular Weight:29,996 Da
NCBI Full Name:60S ribosomal protein L7a
NCBI Synonym Full Names:ribosomal protein L7a
NCBI Official Symbol:RPL7A  
NCBI Official Synonym Symbols:L7A; TRUP; SURF3  
NCBI Protein Information:60S ribosomal protein L7a
UniProt Protein Name:60S ribosomal protein L7a
UniProt Synonym Protein Names:PLA-X polypeptide; Surfeit locus protein 3
Protein Family:60S ribosomal protein
UniProt Gene Name:RPL7A  
UniProt Entry Name:RL7A_HUMAN

Related Products