The Secretagogin Polyclonal Antibody (CAB19615) is a valuable tool for researchers studying the protein secretagogin, which plays a crucial role in calcium signaling and hormone secretion in various tissues. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blot and immunohistochemistry.Secretagogin is known for its involvement in regulating insulin secretion in pancreatic beta cells, making it a promising target for understanding and potentially treating diabetes.
Additionally, secretagogin has been implicated in neurological conditions such as Alzheimer's disease, where it may play a role in synaptic plasticity and memory formation.By using the Secretagogin Polyclonal Antibody, researchers can study the expression and localization of secretagogin in different cell types and tissues, helping to unravel its role in various physiological and pathological processes. This antibody is a valuable tool for investigations in endocrinology, neuroscience, and metabolism research areas.
Product Name:
Secretagogin (SCGN) Rabbit Monoclonal Antibody
SKU:
CAB19615
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 177-276 of human Secretagogin (Secretagogin (SCGN)) (O76038).
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation.
Purification Method:
Affinity purification
Gene ID:
10590
Clone Number:
ARC2196
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Secretagogin (Secretagogin (SCGN)) Rabbit mAb (CAB19615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
