The SCGN Polyclonal Antibody (CAB12897) is a valuable tool for researchers studying Secretagogin (SCGN), a calcium-binding protein involved in insulin secretion and neuroprotection. Raised in rabbits, this antibody is highly specific and reactive with human SCGN samples, making it ideal for use in various research applications, including Western blotting.SCGN plays a crucial role in regulating insulin secretion in pancreatic beta cells and protecting neurons from oxidative stress and excitotoxicity. Dysfunction or dysregulation of SCGN has been implicated in various diseases, including diabetes, neurodegenerative disorders, and cancer.
By targeting SCGN with this antibody, researchers can study its expression levels, localization, and interactions in different cell types, providing valuable insights into its role in health and disease.The SCGN Polyclonal Antibody (CAB12897) is a reliable tool for investigating the function and regulation of SCGN in diverse biological contexts, offering new avenues for therapeutic interventions and drug development targeting this important protein.
Product Name:
Secretagogin (SCGN) Rabbit Polyclonal Antibody
SKU:
CAB12897
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human Secretagogin (Secretagogin (SCGN)) (NP_008929.2).
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation.
Purification Method:
Affinity purification
Gene ID:
10590
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Secretagogin (SCGN) Rabbit pAb (CAB12897) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
