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APC Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL3141)

Datasheet MSDS
SKU AGEL3141
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG1, κ
Clone M/K-2.7
Conjugation APC
€50 - €113

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Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Mouse CD106 Antibody [M/K-2.7]

The APC Anti-Mouse CD106 Antibody (M/K-2.7) offered by AssayGenie is a highly specific and reliable tool for research involving CD106, a cell surface molecule known as vascular cell adhesion molecule 1 (VCAM-1). This antibody is designed for immunohistochemistry, flow cytometry, and other experimental applications requiring detection and analysis of CD106 in mouse samples.CD106, as a key adhesion molecule, plays a crucial role in mediating interactions between leukocytes and vascular endothelial cells, contributing to the inflammatory response and immune cell recruitment. Its involvement in various physiological and pathological processes, such as inflammation, atherosclerosis, and cancer metastasis, underscores the importance of studying its function and regulation.

The APC Anti-Mouse CD106 Antibody (M/K-2.7) demonstrates high specificity and sensitivity in recognizing CD106 in mouse tissues and cells, making it a valuable tool for investigating the role of CD106 in various disease models and immune responses. Researchers studying vascular biology, inflammation, and immune cell interactions will benefit from the reliable performance and accurate detection provided by this antibody.

Product Title:APC Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL3141
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:APC Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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