The Mouse CD106 Monoclonal Antibody (APC-Conjugated, M/K-2.7) from Assay Genie is a powerful tool for researchers studying CD106, also known as VCAM-1. This monoclonal antibody is specifically designed for flow cytometry applications and is conjugated to allophycocyanin (APC), providing a fluorescent signal for easy detection and analysis.CD106 is a cell surface adhesion molecule involved in the regulation of immune responses and inflammation. It plays a crucial role in leukocyte adhesion and migration, making it a key player in various physiological and pathological processes. The APC-conjugated M/K-2.
7 antibody allows for the precise detection and quantification of CD106 expression on different cell types, making it ideal for studies in immunology, vascular biology, and inflammatory diseases.By using the Mouse CD106 Monoclonal Antibody from Assay Genie, researchers can gain valuable insights into the role of CD106 in immune cell interactions, tissue inflammation, and disease pathology. With its high specificity and sensitivity, this antibody is a reliable tool for investigating the function of CD106 in both normal physiological processes and disease states.
Product Title:
APC Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:
AGEL1174
Size:
25µg, 100µg
Clone No:
M/K-2.7
Synonyms:
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
APC Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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