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Anti-APPL Antibody (CAB8932)

SKU:
CAB8932
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Cell Cycle
€139 - €419
Frequently bought together:

Description

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Antibody Name:Anti-APPL Antibody
Antibody SKU:CAB8932
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human APPL
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:PC-12, BxPC-3, Mouse brain, Rat lung
Immunogen:A synthesized peptide derived from human APPL
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:26060
Uniprot:Q9UKG1
Cellular Location:
Calculated MW:85kDa
Observed MW:85KDa
Synonyms:APPL, DIP13alpha, MODY14
Background:The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
UniProt Protein Function:Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
NCBI Summary:The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UKG1
NCBI GenInfo Identifier:61213025
NCBI Gene ID:26060
NCBI Accession:Q9UKG1.1
UniProt Secondary Accession:Q9UKG1,Q9P2B9,
UniProt Related Accession:Q9UKG1
Molecular Weight:83 kDa
NCBI Full Name:DCC-interacting protein 13-alpha
NCBI Synonym Full Names:adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
NCBI Official Symbol:APPL1  
NCBI Official Synonym Symbols:APPL; MODY14; DIP13alpha  
NCBI Protein Information:DCC-interacting protein 13-alpha
UniProt Protein Name:DCC-interacting protein 13-alpha
UniProt Synonym Protein Names:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1
Protein Family:DCC-interacting protein
UniProt Gene Name:APPL1  
Anti-APPL Antibody (CAB8932)Western blot - APPL Rabbit mAb (CAB8932)

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