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UBE4B Rabbit Monoclonal Antibody (CAB0419)

SKU:
CAB0419
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
E4
HDNB1
UBOX3
UFD2
UFD2A
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:UBE4B Rabbit Monoclonal Antibody
SKU:CAB0419
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE4B (O95155).
Sequence:MEEL SADE IRRR RLAR LAGG QTSQ PTTP LTSP QREN PPGP PIAA SAPG PSQS LGLN VHNM TPAT SPIG ASGV AHRS QSSE GVSS LSSS PSNS LETQ SQSL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:E4; UFD2; HDNB1; UBOX3; UFD2A; UBE4B
Positive Sample:SKOV3,K-562,NIH/3T3,Mouse liver,Mouse brain,PC-12,Rat liver,Rat brain
Conjugate:Unconjugated
Cellular Localization:cytoplasm, nucleus
Calculated MW:146kDa
Observed MW:146kDa

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:10277
Clone Number:ARC2503
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using UBE4B antibody (CAB0419) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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