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ATG5 Rabbit Polyclonal Antibody (CAB0203)

SKU:
CAB0203
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-ATG5 Antibody CAB0203
  • Cell Death Antibodies 1 Anti-ATG5 Antibody CAB0203
  • Cell Death Antibodies 1 Anti-ATG5 Antibody CAB0203
  • Cell Death Antibodies 1 Anti-ATG5 Antibody CAB0203
  • Cell Death Antibodies 1 Anti-ATG5 Antibody CAB0203
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ATG5 Rabbit Polyclonal Antibody
SKU:CAB0203
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).
Sequence:MTDD KDVL RDVW FGRI PTCF TLYQ DEIT EREA EPYY LLLP RVSY LTLV TDKV KKHF QKVM RQED ISEI WFEY EGTP LKWH YPIG LLFD LLAS SSAL PWNI TVHF KSFP EKDL LHCP SKDA IEAH FMSC MKEA DALK HKSQ VINE MQKK DHKQ LWMG LQND RFDQ FWAI NRKL MEYP AEEN GFRY IPFR IYQT TTER PFIQ KLFR PVAA DGQL HTLG DLLK EVCP SAID PEDG EKKN QVMI HGIE PMLE TPLQ WLSE HLSY PDNF LHIS IIPQ PTD
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; ATG5
Positive Sample:HepG2,NIH/3T3,K-562,C6,SH-SY5Y
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane.
Calculated MW:32kDa
Observed MW:55kDa

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:9474
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ATG5 Rabbit pAb (CAB0203) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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