The Biotinylated anti-B7-H2 Antibody (HDLA061) is a powerful tool for researchers studying immune regulation and T cell activation. This antibody, produced in rabbits, is highly specific for the B7-H2 protein and is validated for use in various applications, including immunohistochemistry and flow cytometry.B7-H2, also known as inducible costimulator ligand (ICOSL), is a key co-stimulatory molecule that plays a crucial role in T cell activation and immune responses. By targeting B7-H2, researchers can gain valuable insights into the mechanisms underlying immune activation and regulation, particularly in the context of autoimmune diseases, transplantation, and cancer.
The use of the Biotinylated anti-B7-H2 Antibody (HDLA061) offers researchers a reliable and sensitive tool for detecting and analyzing B7-H2 expression in different cell types and tissues. Its high specificity and versatility make it an essential reagent for studies aiming to elucidate the role of B7-H2 in immune function and pathogenesis.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
