The Biotinylated Anti-B7-2 Antibody (HDLA047) is a cutting-edge tool for researchers studying the B7-2 protein, a crucial co-stimulatory molecule involved in immune regulation. This highly specific antibody, developed using advanced techniques, is ideal for use in a variety of applications, including immunohistochemistry and flow cytometry.The B7-2 protein, also known as CD86, plays a pivotal role in T cell activation and immune system function. By targeting B7-2, researchers can gain valuable insights into the mechanisms underlying immune responses and develop new therapeutic strategies for various diseases, including cancer and autoimmune disorders.
This antibody offers researchers a reliable and sensitive tool for detecting and analyzing B7-2 expression in different cell types and tissues. Its high specificity and sensitivity make it an essential component of studies focused on understanding the role of B7-2 in immune regulation and disease pathogenesis.Overall, the Biotinylated Anti-B7-2 Antibody (HDLA047) is a valuable resource for researchers seeking to unravel the complexities of the immune system and develop novel therapies for immune-related disorders.
Product Code:
HDLA047
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM85
Synonyms:
CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
