The Biotinylated Anti-B7-2 Antibody (HDLA048) from Assay Genie is a high-quality research tool specifically designed for the detection and analysis of B7-2 protein expression. This antibody is biotinylated for easy and efficient detection in various immunoassays, including ELISA and flow cytometry.B7-2, also known as CD86, is a co-stimulatory molecule expressed on antigen-presenting cells that plays a critical role in T cell activation and immune response regulation. By targeting B7-2 with this antibody, researchers can gain insights into the mechanisms of immune regulation and potentially develop novel therapeutic strategies for immune-related diseases.
The Biotinylated Anti-B7-2 Antibody (HDLA048) is highly specific and sensitive, ensuring reliable and reproducible results in experimental settings. It is suitable for use with human samples and has been validated for various research applications, making it a valuable tool for studies in immunology, cancer research, and autoimmune disorders.Overall, the Biotinylated Anti-B7-2 Antibody (HDLA048) offers researchers a versatile and reliable option for investigating B7-2 expression and function, advancing our understanding of immune regulation and potential therapeutic targets.
SKU:
HDLA048
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM86
Synonyms:
CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
