The Biotinylated Anti-TIM3 Antibody (HDLA043) is a valuable tool for research in the field of immunology. TIM3, also known as T cell immunoglobulin and mucin domain-containing protein 3, is a cell surface protein that plays a role in regulating immune responses. This antibody, produced using biotinylation technology, is highly specific for TIM3 and is suitable for various applications including Western blotting and immunohistochemistry.The Biotinylated Anti-TIM3 Antibody (HDLA043) binds specifically to TIM3, allowing for the detection and analysis of this important protein in a variety of cell types.
TIM3 is known to be involved in immune tolerance and has been linked to diseases such as cancer and autoimmune disorders. Research into TIM3 and its functions is essential for understanding immune regulation and developing new therapeutic approaches for immune-related diseases.Overall, the Biotinylated Anti-TIM3 Antibody (HDLA043) is a valuable tool for researchers studying immune responses and seeking to unravel the complexities of immune regulation. Its specificity and versatility make it a key component for studies in immunology and cancer research.
SKU:
HDLA043
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM81
Synonyms:
HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
