The BRIP1 Antibody (CAB6804) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blotting and other applications. By binding specifically to the BRIP1 protein, this antibody enables researchers to detect and analyze BRIP1 expression in a variety of cell types, making it an essential component in studies related to DNA repair mechanisms and cancer research.BRIP1, also known as BRCA1-interacting protein 1, plays a crucial role in maintaining genomic stability by participating in DNA repair pathways.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
BRIP1 Antibody
SKU:
CAB6804
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OF, BACH1, FANCJ, BRIP1
Positive Sample:
Jurkat, MCF7
Cellular Localization:
Nucleus.
Calculated MW:
141kDa
Observed MW:
145kDa
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.
Purification Method
Affinity purification
Gene ID
83990
RRID
AB_2767385
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using BRIP1 Rabbit pAb (CAB6804) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
