The CD116/GM-CSFRalpha Monoclonal Antibody (CAB23001) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced in mice, demonstrates high specificity and sensitivity for human samples, making it ideal for use in a variety of research applications.The GM-CSFR, also known as CD116, plays a key role in the differentiation and activation of myeloid cells, making it a significant target for studies in immunology, hematopoiesis, and cancer research. By specifically targeting the CD116 protein, this monoclonal antibody allows for accurate detection and analysis of GM-CSFR expression in different cell types, providing valuable insights into its function and potential therapeutic applications.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CD116/GM-CSFRalpha Monoclonal Antibody
SKU:
CAB23001
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC59284
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:5000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Secreted, Cell Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:
27kDa/33kDa/38kDa/44kDa/46kDa/50kDa
Observed MW:
70-80kDa
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
Purification Method
Affinity purification
Gene ID
1438
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CD116/GM-CSFRα Rabbit mAb (CAB23001) at 1:1000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): 293T. Exposure time: 20 s.
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