Anti-CLEC4D Antibody (CAB2697)
- SKU:
- CAB2697
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-CLEC4D Antibody |
| Antibody SKU: | CAB2697 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_525126.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:1000 - 1:4000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse spleen, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_525126.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CLVT HHNF SRCK RGTG VHKL EHHA KLKC IKEK SELK SAEG STWN CCPI DWRA FQSN CYFP LTDN KTWA ESER NCSG MGAH LMTI STEA EQNF IIQF LDRR LSYF LGLR DENA KGQW RWVD QTPF NPRR VFWH KNEP DNSQ GENC VVLV YNQD KWAW NDVP CNFE ASRI CKIP GTTL N |
| Gene ID: | 338339 |
| Uniprot: | Q8WXI8 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 24kDa |
| Observed MW: | 27KDa |
| Synonyms: | CLEC4D, CD368, CLEC-6, CLEC6, CLECSF8, MCL, MPCL |
| Background: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. |
| UniProt Protein Function: | CLEC4D: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: integral to membrane Molecular Function:carbohydrate binding Biological Process: innate immune response |
| UniProt Code: | Q8WXI8 |
| NCBI GenInfo Identifier: | 73916933 |
| NCBI Gene ID: | |
| NCBI Accession: | Q8WXI8.2 |
| Molecular Weight: | |
| NCBI Full Name: | C-type lectin domain family 4 member D |
| UniProt Protein Name: | C-type lectin domain family 4 member D |
| UniProt Synonym Protein Names: | C-type lectin superfamily member 8; C-type lectin-like receptor 6; CLEC-6 |
| UniProt Gene Name: | CLEC4DÂ Â |
| UniProt Entry Name: | CLC4D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CLEC4D Rabbit pAb (CAB2697) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of mouse spleen using CLEC4D Rabbit pAb (CAB2697) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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