COA1 Antibody (PACO25404)
- SKU:
- PACO25404
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | COA1 Antibody (PACO25404) |
| Antibody SKU: | PACO25404 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO25404 at dilution of 1:100. |
 | Immunofluorescent analysis of U251 cells using PACO25404 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO25404 at dilution of 1:100. |
| Background: | Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV. |
| Synonyms: | Cytochrome c oxidase assembly factor 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa), COA1, C7orf44 MITRAC15 |
| UniProt Protein Function: | COA1: Belongs to the COA1 family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7p13Cellular Component: cytoplasm; integral to mitochondrial inner membrane; mitochondrionMolecular Function: RNA binding; structural constituent of ribosomeBiological Process: mitochondrial respiratory chain complex I assembly; mitochondrial respiratory chain complex IV assembly; translation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9GZY4 |
| NCBI GenInfo Identifier: | 90855771 |
| NCBI Gene ID: | 55744 |
| NCBI Accession: | NP_060694.2 |
| UniProt Secondary Accession: | Q9GZY4,Q9HAB7, Q9NVD2, A6NJU8, A8KAH8 |
| UniProt Related Accession: | Q9GZY4 |
| Molecular Weight: | 16,694 Da |
| NCBI Full Name: | cytochrome c oxidase assembly factor 1 homolog |
| NCBI Synonym Full Names: | cytochrome c oxidase assembly factor 1 homolog |
| NCBI Official Symbol: | COA1Â Â |
| NCBI Official Synonym Symbols: | C7orf44; MITRAC15Â Â |
| NCBI Protein Information: | cytochrome c oxidase assembly factor 1 homolog |
| UniProt Protein Name: | Cytochrome c oxidase assembly factor 1 homolog |
| UniProt Synonym Protein Names: | Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa |
| Protein Family: | Cytochrome c oxidase assembly factor |
| UniProt Gene Name: | COA1Â Â |
| UniProt Entry Name: | COA1_HUMAN |