The COLEC12 Antibody (CAB10422) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for Western blot applications. By binding to the Collectin-12 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in immunology and cancer research.Collectin-12, also referred to as CL-P1, is a member of the collectin family of proteins that are involved in innate immunity and inflammation. Known for its ability to bind to pathogens and activate the immune response, Collectin-12 is a crucial component in the body's defense against infection and disease.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
COLEC12 Antibody
SKU:
CAB10422
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CLP1, NSR2, SRCL, SCARA4, COLEC12
Positive Sample:
A-549, U-87MG, 293T, Mouse lung, Mouse liver
Cellular Localization:
Membrane, Single-Pass Type Ii Membrane Protein.
Calculated MW:
82kDa
Observed MW:
110kDa
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Purification Method
Affinity purification
Gene ID
81035
RRID
AB_2757969
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using COLEC12 Rabbit pAb (CAB10422) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
