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CTBP2 Rabbit Polyclonal Antibody (CAB16826)

SKU:
CAB16826
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CTBP2 Rabbit Polyclonal Antibody
SKU:CAB16826
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human CTBP2 (NP_001320.1).
Sequence:SEPF SFAQ GPLK DAPN LICT PHTA WYSE QASL EMRE AAAT EIRR AITG RIPE SLRN CVNK EFFV TSAP WSVI DQQA IHPE LNGA TYRY PPGI VGVA PGGL PAAM EGII PGGI PVTH NLPT VAHP SQAP SPNQ PTKH GDNR EHPN EQ
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:CTBP2
Positive Sample:HeLa,COS-7,BxPC-3,NIH/3T3,Mouse brain,Rat brain
Cellular Localization:Cell junction, Nucleus, synapse.
Calculated MW:49kDa
Observed MW:49kDa

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:1488
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CTBP2 Rabbit pAb (CAB16826) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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