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DAP Kinase 1 (DAPK1) Rabbit Monoclonal Antibody (CAB11459)

Datasheet MSDS
SKU CAB11459
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms DAPK, ROCO3, DAP Kinase 1 (DAPK1)
Research Use Cell Death
$173 - $603

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Description

system_update_altDatasheetsystem_update_altMSDS

DAP Kinase 1 (DAPK1) Monoclonal Antibody (CAB11459)

The DAP Kinase 1 (DAPK1) Monoclonal Antibody (CAB11459) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting DAP Kinase 1 in various experimental settings, including Western blot applications.DAP Kinase 1, a pro-apoptotic protein, is known for its role in promoting programmed cell death and inhibiting tumor growth. Dysregulation of DAP Kinase 1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:DAP Kinase 1 (DAPK1) Monoclonal Antibody
SKU:CAB11459
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC0601
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:DFIR RLLV KDPK KRMT IQDS LQHP WIKP KDTQ QALS RKAS AVNM EKFK KFAA RKKW KQSV RLIS LCQR LSRS FLSR SNMS VARS DDTL DEED SFVM KAII H
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DAPK, ROCO3, DAP Kinase 1 (DAPK1)
Positive Sample:OVCAR3, Mouse lung
Cellular Localization:Cytoplasm, Cytoskeleton, Cytoskeleton.
Calculated MW:160kDa
Observed MW:160kDa

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID1612
RRIDAB_2861570
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DAP Kinase 1 (DAPK1) Rabbit mAb (CAB11459) at 1：1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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