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Desmoplakin Rabbit Polyclonal Antibody (CAB13299)

SKU:
CAB13299
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 3 Anti-DSP Antibody CAB13299
  • Cell Biology Antibodies 3 Anti-DSP Antibody CAB13299
  • Cell Biology Antibodies 3 Anti-DSP Antibody CAB13299
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Desmoplakin Rabbit Polyclonal Antibody
SKU:CAB13299
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 2609-2830 of human Desmoplakin (NP_004406.2).
Sequence:FSDT LEES SPIA AIFD TENL EKIS ITEG IERG IVDS ITGQ RLLE AQAC TGGI IHPT TGQK LSLQ DAVS QGVI DQDM ATRL KPAQ KAFI GFEG VKGK KKMS AAEA VKEK WLPY EAGQ RFLE FQYL TGGL VDPE VHGR ISTE EAIR KGFI DGRA AQRL QDTS SYAK ILTC PKTK LKIS YKDA INRS MVED ITGL RLLE AASV SSKG LPSP YNMS SAPG SRSG SR
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:DP; DCWHKTA; Desmoplakin
Positive Sample:HepG2,Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cytoplasm, cytoskeleton, desmosome.
Calculated MW:332kDa
Observed MW:260-332kDa

This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:1832
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Desmoplakin Rabbit pAb (CAB13299) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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