The ELP3 Polyclonal Antibody (CAB9877) is a powerful tool for researchers studying the ELP3 protein, a key player in gene transcription and protein translation processes. This antibody, generated in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to the ELP3 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in molecular biology and gene regulation.ELP3, also known as elongator complex protein 3, is involved in acetyltransferase activity and plays a crucial role in histone modifications and RNA polymerase II transcription.
Its involvement in various cellular processes underscores its importance in understanding gene expression regulation and protein synthesis. Research on ELP3 is vital for unraveling the molecular mechanisms underlying diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. By elucidating the function of ELP3, researchers can pave the way for targeted therapies and treatment strategies in these pathological conditions.
Product Name:
KAT9/Elp3 Rabbit Polyclonal Antibody
SKU:
CAB9877
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KAT9/Elp3 (NP_060561.3).
Enables acetyltransferase activity and phosphorylase kinase regulator activity. Involved in regulation of transcription by RNA polymerase II and tRNA wobble uridine modification. Located in cytosol and nucleolus. Part of elongator holoenzyme complex.
Purification Method:
Affinity purification
Gene ID:
55140
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using KAT9/Elp3 Rabbit pAb (CAB9877) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
