The ESRRA Monoclonal Antibody (CAB4176) is a high-quality antibody developed for reliable detection and analysis of target proteins. ERRα is a transcription factor that plays a crucial role in regulating energy metabolism, cell proliferation, and differentiation. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting ERRα in human samples.Validated for use in applications such as Western blot and immunohistochemistry, this antibody enables precise detection and analysis of ERRα in a variety of cell types and tissue samples.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
ESRRA Monoclonal Antibody
SKU:
CAB4176
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0919
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ERR1, ERRa, ESRL1, NR3B1, ERRalpha, ESRRA
Positive Sample:
HeLa, 293T, Mouse brain
Cellular Localization:
Nucleus, Cytoplasm.
Calculated MW:
46kDa
Observed MW:
48-50kDa
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
Purification Method
Affinity purification
Gene ID
2101
RRID
AB_2863203
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ESRRA Rabbit mAb (CAB4176) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 3min.
