Description
FOXK1 Transcription Factor Activity Assay
The FOXK1 Transcription Factor Activity Assay Kit is a powerful tool for measuring the transcriptional activity of FOXK1 in cell lysates and nuclear extracts. This kit provides high sensitivity and specificity, allowing for precise and reliable results in a variety of research applications.FOXK1 is a transcription factor that plays a key role in regulating gene expression involved in cell growth, differentiation, and development. Dysregulation of FOXK1 has been implicated in various diseases, including cancer, making it a valuable target for therapeutic intervention.
By accurately measuring FOXK1 transcriptional activity, researchers can gain valuable insights into the molecular mechanisms underlying disease progression and potentially identify new therapeutic targets. With its ease of use and robust performance, the FOXK1 Transcription Factor Activity Assay Kit is an essential tool for advancing research in the field of transcriptional regulation.
| Product Name: | FOXK1 Transcription Factor Activity Assay |
| Product Code: | TFAB00113 |
| Target: | FOXK1 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie FOXK1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | FOXK1: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 7p22.1 Cellular Component: nucleus Molecular Function:protein binding Biological Process: anatomical structure morphogenesis; cell differentiation; muscle development; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent |
| UniProt Code: | P85037 |
| NCBI GenInfo Identifier: | 118572324 |
| NCBI Gene ID: | 221937 |
| NCBI Accession: | P85037.1 |
| UniProt Secondary Accession: | P85037,P42128, |
| UniProt Related Accession: | P85037 |
| Molecular Weight: | 59,702 Da |
| NCBI Full Name: | Forkhead box protein K1 |
| NCBI Synonym Full Names: | forkhead box K1 |
| NCBI Official Symbol: | FOXK1 |
| NCBI Official Synonym Symbols: | FOXK1L |
| NCBI Protein Information: | forkhead box protein K1 |
| UniProt Protein Name: | Forkhead box protein K1 |
| UniProt Synonym Protein Names: | Myocyte nuclear factor; MNF |
| Protein Family: | Forkhead box protein |
| UniProt Gene Name: | FOXK1 |
| UniProt Entry Name: | FOXK1_HUMAN |
