Description
JunB Transcription Factor Activity Assay
The JunB Transcription Factor Activity Assay Kit is specifically designed for the sensitive and accurate detection of JunB transcription factor activity in various biological samples. This kit offers high specificity and precision, providing researchers with reliable and reproducible results for their experiments.JunB is a key transcription factor that plays a crucial role in regulating gene expression and cellular processes such as proliferation, differentiation, and apoptosis. Abnormalities in JunB activity have been implicated in various diseases, including cancer, inflammatory disorders, and immune dysfunction, highlighting the importance of studying JunB in biological research.
With its easy-to-use format and robust performance, the JunB Transcription Factor Activity Assay Kit is an essential tool for investigating the function of JunB in different cellular pathways and disease contexts. Researchers can confidently rely on this kit to accurately measure JunB activity and gain valuable insights into its role in health and disease.
| Product Name: | JunB Transcription Factor Activity Assay |
| Product Code: | TFAB00079 |
| Target: | JunB |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie JunB transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation |
| UniProt Code: | P17275 |
| NCBI GenInfo Identifier: | 135304 |
| NCBI Gene ID: | 3726 |
| NCBI Accession: | P17275.1 |
| UniProt Secondary Accession: | P17275,Q96GH3, |
| UniProt Related Accession: | P17275 |
| Molecular Weight: | 35,879 Da |
| NCBI Full Name: | Transcription factor jun-B |
| NCBI Synonym Full Names: | JunB proto-oncogene, AP-1 transcription factor subunit |
| NCBI Official Symbol: | JUNB |
| NCBI Official Synonym Symbols: | AP-1 |
| NCBI Protein Information: | transcription factor jun-B |
| UniProt Protein Name: | Transcription factor jun-B |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | JUNB |
| UniProt Entry Name: | JUNB_HUMAN |
