JunB Transcription Factor Activity Assay

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SKU:
TFAB00079
€599

Description

ELISA Kit Technical ManualMSDS

JunB Transcription Factor activity assay

Product Description:The ELISA Genie JunB transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:N/A
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

JunB Transcription Factor activity assay Protein Information

UniProt Protein Function:JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex

Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding

Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation

UniProt Code:P17275
NCBI GenInfo Identifier:135304
NCBI Gene ID:3726
NCBI Accession:P17275.1
UniProt Secondary Accession:P17275,Q96GH3,
UniProt Related Accession:P17275
Molecular Weight:35,879 Da
NCBI Full Name:Transcription factor jun-B
NCBI Synonym Full Names:JunB proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol:JUNB
NCBI Official Synonym Symbols:AP-1
NCBI Protein Information:transcription factor jun-B
UniProt Protein Name:Transcription factor jun-B
Protein Family:Transcription factor
UniProt Gene Name:JUNB
UniProt Entry Name:JUNB_HUMAN
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