Description
JunB (Phospho-Ser259)Transcription Factor Activity Assay
The JUNB Phospho-Ser259 Transcription Factor Activity Assay is a cutting-edge kit designed to accurately measure the activity levels of JUNB protein in cell lysates. This assay kit features high specificity and sensitivity, providing researchers with reliable and reproducible results for a variety of research applications.JUNB is a key transcription factor involved in regulating gene expression and plays a critical role in various cellular processes, including cell growth, differentiation, and apoptosis. The phosphorylation of JUNB at serine 259 is known to modulate its transcriptional activity, making it an important signaling event in various biological pathways.
The JUNB Phospho-Ser259 Transcription Factor Activity Assay can be a valuable tool for studying the role of JUNB in different cellular processes, as well as for investigating the impact of phosphorylation on its transcriptional activity. This kit is ideal for researchers interested in understanding the molecular mechanisms underlying gene regulation and transcriptional control.
| Product Name: | JunB (Phospho-Ser259)Transcription Factor Activity Assay |
| Product Code: | TFAB00010 |
| Target: | JunB (Phospho-Ser259) |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie JunB (Phospho-Ser259) transcription factor activity assay allows for the detection and qualitative analysis of JunB (Phospho-Ser259) active transcription factors in eukaryotic nuclear or cell lysates.
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation |
| UniProt Code: | P17275 |
| NCBI GenInfo Identifier: | 135304 |
| NCBI Gene ID: | 3726 |
| NCBI Accession: | P17275.1 |
| UniProt Secondary Accession: | P17275,Q96GH3, |
| UniProt Related Accession: | P17275 |
| Molecular Weight: | 35,879 Da |
| NCBI Full Name: | Transcription factor jun-B |
| NCBI Synonym Full Names: | JunB proto-oncogene, AP-1 transcription factor subunit |
| NCBI Official Symbol: | JUNB |
| NCBI Official Synonym Symbols: | AP-1 |
| NCBI Protein Information: | transcription factor jun-B |
| UniProt Protein Name: | Transcription factor jun-B |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | JUNB |
| UniProt Entry Name: | JUNB_HUMAN |
