Phospho-JUNB-S79 pAb (CABP0376)

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CABP0376
  • Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-JUNB-S79 antibody (CABP0376).
  • Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-JUNB-S79 antibody (CABP0376).
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Description

Technical Manual

Phospho-JUNB-S79 Rabbit Polyclonal Antibody

Product Name:Phospho-JUNB-S79 Rabbit Polyclonal Antibody
Product SKU:CABP0376
Size:100 uL
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Background:

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Immunogen:A phospho specific peptide corresponding to residues surrounding S79 of human JUNB
Sequence:

Email for sequence

Gene ID:3726
Swiss Prot:P17275
Synonyms:JUNB; AP-1
Calculated MW:35kDa
Observed MW:
Reactivity:Human, Mouse, Rat
Application:IHC IF
Recommended Dilution:IHC 1:50 - 1:100 IF 1:100 - 1:200
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunohistochemistry Immunofluorescence 
Positive Samples:
Cellular Location:Nucleus

Product Images

Phospho-JUNB-S79 pAb (CABP0376)

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-JUNB-S79 antibody (CABP0376).

Phospho-JUNB-S79 pAb (CABP0376)

Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-JUNB-S79 antibody (CABP0376).

Uniprot Information

UniProt Protein Function:JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex

Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding

Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation

UniProt Code:P17275
NCBI GenInfo Identifier:135304
NCBI Gene ID:3726
NCBI Accession:P17275.1
UniProt Secondary Accession:P17275,Q96GH3,
UniProt Related Accession:P17275
Molecular Weight:35,879 Da
NCBI Full Name:Transcription factor jun-B
NCBI Synonym Full Names:JunB proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol:JUNB 
NCBI Official Synonym Symbols:AP-1 
NCBI Protein Information:transcription factor jun-B
UniProt Protein Name:Transcription factor jun-B
Protein Family:Transcription factor
UniProt Gene Name:JUNB 
UniProt Entry Name:JUNB_HUMAN
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Additional Information

Product type:
Antibody
Application:
IHC
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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