Description
OCT2 Transcription Factor Activity Assay
Based on the information provided in the URL, here is a product description:The OCT2 Transcription Factor Activity Assay is a cutting-edge research tool designed for the precise measurement of OCT2 transcription factor activity in biological samples. This assay kit offers unparalleled sensitivity and specificity, allowing for accurate and reproducible results across a wide range of experimental conditions.OCT2 is a key transcription factor with a crucial role in regulating gene expression and cellular function. Its activity is known to impact various biological processes, including cell proliferation, differentiation, and immune responses.
By measuring OCT2 activity, researchers can gain valuable insights into the molecular mechanisms underlying these processes and potentially identify novel therapeutic targets.Whether investigating the role of OCT2 in cancer progression, immune system function, or developmental biology, the OCT2 Transcription Factor Activity Assay provides researchers with a powerful tool to advance their understanding of this essential transcription factor. With its user-friendly protocol and reliable performance, this assay kit is a valuable addition to any laboratory conducting research in the field of molecular biology and gene regulation.
| Product Name: | OCT2 Transcription Factor Activity Assay |
| Product Code: | TFAB00150 |
| Target: | OCT2 |
| Synonyms: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie Oct2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein domain specific binding; sequence-specific DNA binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response |
| NCBI Summary: | The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P09086 |
| NCBI GenInfo Identifier: | 123402 |
| NCBI Gene ID: | 5452 |
| NCBI Accession: | P09086.3 |
| UniProt Secondary Accession: | P09086,Q16648, Q7M4M8, Q9BRS4, |
| UniProt Related Accession: | P09086 |
| Molecular Weight: | 400 |
| NCBI Full Name: | POU domain, class 2, transcription factor 2 |
| NCBI Synonym Full Names: | POU class 2 homeobox 2 |
| NCBI Official Symbol: | POU2F2 |
| NCBI Official Synonym Symbols: | OCT2; OTF2; Oct-2 |
| NCBI Protein Information: | POU domain, class 2, transcription factor 2; OTF-2; homeobox protein; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 |
| UniProt Protein Name: | POU domain, class 2, transcription factor 2 |
| UniProt Synonym Protein Names: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2 |
| Protein Family: | POU domain, class 2, transcription factor |
| UniProt Gene Name: | POU2F2 |
| UniProt Entry Name: | PO2F2_HUMAN |
