Description
TBX2 Transcription Factor Activity Assay
The TBX2 Transcription Factor Activity Assay is a cutting-edge kit designed for the precise measurement of TBX2 transcription factor activity in cell lysates. With its exceptional sensitivity and specificity, this assay guarantees accurate and consistent results, making it a valuable tool for a variety of research studies.TBX2 is a crucial transcription factor that plays a pivotal role in regulating gene expression and cell growth. Dysregulation of TBX2 has been linked to various diseases, including cancer and developmental disorders.
Therefore, the TBX2 Transcription Factor Activity Assay is essential for studying the biological functions of TBX2 and identifying potential therapeutic targets for related conditions.Don't miss out on the opportunity to advance your research with the TBX2 Transcription Factor Activity Assay. Order yours today and unlock new insights into the intricate mechanisms of gene regulation and cellular processes.
| Product Name: | TBX2 Transcription Factor Activity Assay |
| Product Code: | TFAB00169 |
| Target: | TBX2 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie TBX2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | TBX2: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 17q23.2 Cellular Component: nucleus Molecular Function:DNA binding; protein binding; sequence-specific DNA binding Biological Process: cardiac muscle development; cell aging; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic heart tube development; heart looping; muscle cell fate determination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; regulation of heart contraction |
| NCBI Summary: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13207 |
| NCBI GenInfo Identifier: | 294862490 |
| NCBI Gene ID: | 6909 |
| NCBI Accession: | Q13207.3 |
| UniProt Secondary Accession: | Q13207,Q16424, Q7Z647, |
| UniProt Related Accession: | Q13207 |
| Molecular Weight: | 75,066 Da |
| NCBI Full Name: | T-box transcription factor TBX2 |
| NCBI Synonym Full Names: | T-box 2 |
| NCBI Official Symbol: | TBX2 |
| NCBI Protein Information: | T-box transcription factor TBX2 |
| UniProt Protein Name: | T-box transcription factor TBX2 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | TBX2 |
| UniProt Entry Name: | TBX2_HUMAN |
