ELF1 Transcription Factor Activity Assay

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SKU:
TFAB00094
€599

Description

ELISA Kit Technical ManualMSDS

ELF1 Transcription Factor activity assay

Product Description:The ELISA Genie ELF1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:E74-like factor 1
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

ELF1 Transcription Factor activity assay Protein Information

UniProt Protein Function:Elf-1: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. Belongs to the ETS family.
UniProt Protein Details:

Protein type:DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q13

Cellular Component: nucleoplasm; nucleus

Molecular Function:protein binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; regulation of cytokine production

NCBI Summary:This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
UniProt Code:P32519
NCBI GenInfo Identifier:212288097
NCBI Gene ID:1997
NCBI Accession:P32519.2
UniProt Secondary Accession:P32519,Q8N6F6, Q9UDE1, B4E2I5, E9PDQ9,
UniProt Related Accession:P32519
Molecular Weight:64,929 Da
NCBI Full Name:ETS-related transcription factor Elf-1
NCBI Synonym Full Names:E74-like factor 1 (ets domain transcription factor)
NCBI Official Symbol:ELF1
NCBI Protein Information:ETS-related transcription factor Elf-1
UniProt Protein Name:ETS-related transcription factor Elf-1
UniProt Synonym Protein Names:E74-like factor 1
Protein Family:ETS-related transcription factor
UniProt Gene Name:ELF1
UniProt Entry Name:ELF1_HUMAN
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