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GenieFluor 488 Anti-Mouse CD117 Antibody [2B8] (AGEL2179)

Datasheet MSDS
SKU AGEL2179
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone 2B8
Conjugation AF488
€102 - €300

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Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 488 Anti-Mouse CD117 Antibody [2B8]

The GenieFluor 488 Anti-Mouse CD117 Antibody (2B8) is a cutting-edge tool in immunology research, specifically designed for detecting and analyzing CD117, a cell surface receptor involved in various cellular processes. This high-quality antibody, derived from mouse sources, exhibits strong reactivity and specificity towards mouse CD117 samples, making it an essential component for studies focusing on hematopoiesis, stem cell biology, and cancer research.CD117, also known as c-kit, is a crucial marker for identifying hematopoietic stem cells and certain types of cancer cells.

By targeting CD117, researchers can gain valuable insights into the regulation of cell growth, differentiation, and survival, offering new avenues for therapeutic interventions in conditions such as leukemia and solid tumors. The GenieFluor 488 Anti-Mouse CD117 Antibody (2B8) enables precise visualization and quantification of CD117 expression in diverse cell types, facilitating detailed investigations into the roles of this receptor in health and disease.

Product Title:GenieFluor 488 Anti-Mouse CD117 Antibody [2B8]
SKU:AGEL2179
Size:50 Tests, 100 Tests, 200 Tests
Clone No:2B8
Synonyms:Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05532
Gene ID:16590
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
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