Description

GenieFluor 647 Anti-Mouse CD117 Antibody [2B8]

The GenieFluor 647 Anti-Mouse CD117 Antibody (2B8) is a powerful tool for researchers studying the CD117 protein, also known as c-kit. This antibody, specifically designed for use in mouse samples, is raised against CD117 to enable precise detection and analysis in various tissues and cell types.CD117 is a transmembrane receptor tyrosine kinase that plays a crucial role in various biological processes, including hematopoiesis, stem cell maintenance, and cell differentiation. It is particularly important in the development and function of hematopoietic stem cells, making it a key target for research in areas such as cancer, blood disorders, and regenerative medicine.

The GenieFluor 647 Anti-Mouse CD117 Antibody (2B8) offers exceptional specificity and sensitivity, making it ideal for applications such as immunofluorescence, flow cytometry, and immunohistochemistry. Its ability to specifically recognize and bind to CD117 allows researchers to study the expression, localization, and function of this critical protein with precision and accuracy.By utilizing this antibody, researchers can gain valuable insights into the role of CD117 in various biological processes and diseases, ultimately advancing our understanding of hematopoiesis, stem cell biology, and potential therapeutic interventions.

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Product Title:	GenieFluor 647 Anti-Mouse CD117 Antibody [2B8]
SKU:	AGEL2182
Size:	25µg, 100µg
Clone No:	2B8
Synonyms:	Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:	Rat
Reactivity:	Mouse
Application:	FCM

Isotype:	Rat IgG2b, κ
Isotype Control:	Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:	Liquid
Conjugation:	Genie Fluor647
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:

Swissprot:	P05532
Gene ID:	16590
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

GenieFluor 647 Anti-Mouse CD117 Antibody [2B8] (AGEL2182)

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Description