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Glycophorin C (GYPC) Rabbit Monoclonal Antibody (CAB11472)

SKU:
CAB11472
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Glycophorin C (GYPC) Rabbit Monoclonal Antibody
SKU:CAB11472
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 49-128 of human Glycophorin C (GYPC) (P04921).
Sequence:METS TPTI MDIV VIAG VIAA VAIV LVSL LFVM LRYM YRHK GTYH TNEA KGTE FAES ADAA LQGD PALQ DAGD SSRK EYFI
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2'; Glycophorin C (GYPC)
Positive Sample:K-562,Mouse liver,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Single-pass type III membrane protein.
Calculated MW:14kDa
Observed MW:30-40kDa

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:2995
Clone Number:ARC0605
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Glycophorin C (GYPC) Rabbit mAb (CAB11472) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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