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HMBS Rabbit Monoclonal Antibody (CAB11701)

SKU:
CAB11701
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Metabolism
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HMBS Rabbit Monoclonal Antibody
SKU:CAB11701
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human HMBS (P08397).
Sequence:ERAF LRHL EGGC SVPV AVHT AMKD GQLY LTGG VWSL DGSD SIQE TMQA TIHV PAQH EDGP EDDP QLVG ITAR NIPR GPQL AAQN LGIS LANL LLSK GAKN I
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:UPS; PBGD; PORC; PBG-D; HMBS
Positive Sample:Hep G2,Mouse kidney,Mouse heart,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:39kDa
Observed MW:45-50kDa

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Purification Method:Affinity purification
Gene ID:3145
Clone Number:ARC0685
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using HMBS Rabbit mAb (CAB11701) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.

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