Description
Human CD272/BTLA Recombinant Protein (C-His)
Human CD272/BTLA Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Ser150, with a C-terminal His tag. Predicted molecular weight: 18.22 kDa. Purity: >85% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. For research use only.
May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells.
| Product Name: | Human CD272/BTLA Recombinant Protein (C-His) |
| SKU: | GXRP02507 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Ser150 |
| Calculated MW: | 18.22 kDa |
| UniProt: | Q7Z6A9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >85% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
