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FITC Anti-Human CD45 Antibody [HI30] (AGEL1677)

Datasheet MSDS
SKU AGEL1677
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone HI30
Conjugation FITC
€30 - €123

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody (FITC Conjugated) is a powerful tool for immunology research, specifically targeting the CD45 protein, a key marker for immune cell identification. This antibody, clone HI30-AGEL1677, is engineered for precise detection and analysis of CD45 in human samples, making it an essential component for studies in immunophenotyping and cell signaling pathways.CD45, also known as leukocyte common antigen, plays a vital role in immune cell development, activation, and function. By specifically binding to CD45, this monoclonal antibody allows researchers to accurately characterize different immune cell populations, facilitating a deeper understanding of immune responses and diseases such as cancer, autoimmune disorders, and infectious diseases.

The FITC conjugation of this antibody offers the advantage of fluorescence detection, enabling flow cytometry and microscopy applications for high-resolution imaging and quantification of CD45-expressing cells. Its versatility and reliability make it an indispensable tool for immunologists and researchers exploring the intricacies of immune system dynamics and pathology.Choose the Human CD45 Monoclonal Antibody (FITC Conjugated) for robust and accurate detection of CD45 in human samples, advancing your research in immunology, cancer biology, and immune-related disorders.

Product Title:FITC Anti-Human CD45 Antibody [HI30]
SKU:AGEL1677
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
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