Description

Purified Anti-Human CD45 Antibody [HI30]

The Purified Anti-Human CD45 Antibody (HI30) offered by AssayGenie is a valuable tool for researchers studying human immune cells and their functions. This antibody specifically targets the CD45 antigen, a key cell surface protein found on all human leukocytes. The HI30 antibody is purified and validated for use in various applications, including flow cytometry, immunohistochemistry, and immunoprecipitation. Its high specificity and reactivity with human samples make it a reliable choice for experiments aiming to identify, isolate, and analyze different immune cell populations.CD45 plays a crucial role in T-cell and B-cell receptor signaling, making it an essential marker for distinguishing between lymphocyte subsets.

By using the Purified Anti-Human CD45 Antibody (HI30), researchers can gain insights into the activation status and distribution of immune cells in both normal and pathological conditions.Whether investigating immune responses in infectious diseases, autoimmune disorders, or cancer immunotherapy, this antibody provides a valuable tool for uncovering the complexities of the human immune system. Upgrade your research capabilities with the Purified Anti-Human CD45 Antibody (HI30) from AssayGenie and unlock new discoveries in immunology and beyond.

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Product Title:	Purified Anti-Human CD45 Antibody [HI30]
SKU:	AGEL3508
Size:	25µg, 100µg
Clone No:	HI30
Synonyms:	Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	Unconjugated
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Swissprot:	P08575
Gene ID:	5788
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

Purified Anti-Human CD45 Antibody [HI30] (AGEL3508)

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Description