Description
Human ITGB7 Recombinant Protein (C-Strep)
Human ITGB7 Recombinant Protein (C-Strep) is a recombinant protein expressed in mammalian cells, spanning Met1-His723, with a C-terminal Strep tag. Predicted molecular weight: 83.14 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from PBS pH7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: SDS-PAGE, Western blot, ELISA and immunogen. Integrin beta-7 (ITGB7) is a ~86 kDa protein. Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable). For research use only.
Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component (Probable). It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin (Probable). Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin (Probable).
| Product Name: | Human ITGB7 Recombinant Protein (C-Strep) |
| SKU: | GXRP08470 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Integrin beta-7, Gut homing receptor beta subunit, ITGB7 |
| Tag: | C-Strep |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-His723 |
| Calculated MW: | 83.14 kDa |
| UniProt: | P26010 |
| Applications: | SDS-PAGE, WB, ELISA, Immunogen |
| Purity: | >95% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from PBS pH7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
