Description
Human LRP4 Recombinant Protein (N-GST)
Human LRP4 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Arg1610-Arg1885, with an N-terminal GST tag. Predicted molecular weight: 56.68 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Low-density lipoprotein receptor-related protein 4 (LRP4) is a ~212 kDa protein. Mediates SOST-dependent inhibition of bone formation. For research use only.
Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex.
| Product Name: | Human LRP4 Recombinant Protein (N-GST) |
| SKU: | GXRP00220 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Low-density lipoprotein receptor-related protein 4, MEGF7, LRP10, LRP4, LRP-4, KIAA0816, Multiple epidermal growth factor-like domains 7 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Arg1610-Arg1885 |
| Calculated MW: | 56.68 kDa |
| UniProt: | O75096 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
