Human TDGF1/CRIPTO (BIIB015) Antibody (ADC, Payload-Free)
Human TDGF1/CRIPTO (BIIB015) Antibody (ADC, Payload-Free) is a research-grade biosimilar monoclonal antibody targeting Cripto-1 growth factor. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Supplied as the antibody component without the cytotoxic payload. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Protein Cripto (TDGF1) is a ~21 kDa protein. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
Product Name:
Human TDGF1/CRIPTO (BIIB015) Antibody (ADC, Payload-Free)
SKU:
GXBS01214
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
BIIB015
Target:
Cripto-1 growth factor
Isotype:
IgG
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FCM, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
BIIB015
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
