Description
IKZF2 Transcription Factor Activity Assay
The IKZF2 Transcription Factor Activity Assay Kit is a vital tool for studying the activity of IKZF2 in research settings. IKZF2, also known as Helios, is a transcription factor that plays a critical role in regulating gene expression and immune system function. This assay kit offers high sensitivity and precision, allowing for accurate measurement of IKZF2 activity in various sample types such as cell lysates and tissue homogenates. Researchers can rely on the reproducibility of results obtained with this kit, ensuring robust data for their experiments.
Understanding the activity of IKZF2 is essential for investigating its role in immune response, autoimmune diseases, and cancer development. By using this assay kit, researchers can gain valuable insights into the function of IKZF2 and its potential as a therapeutic target in various diseases. Overall, the IKZF2 Transcription Factor Activity Assay Kit is a versatile and reliable tool for studying IKZF2 function, opening up new possibilities for research and drug discovery in the field of immunology and beyond.
| Product Name: | IKZF2 Transcription Factor Activity Assay |
| Product Code: | TFAB00130 |
| Target: | IKZF2 |
| Synonyms: | Ikaros family zinc finger protein 2 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie IKZF2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Associates with Ikaros at centromeric heterochromatin. |
| NCBI Summary: | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UKS7 |
| NCBI GenInfo Identifier: | 116242509 |
| NCBI Gene ID: | 22807 |
| NCBI Accession: | Q9UKS7.2 |
| UniProt Secondary Accession: | Q9UKS7,Q53YJ5, Q6PQC5, Q6PQC6, Q6PQC7, Q6PQC8, Q6PQD0 Q6PQD1, Q8N6S1, |
| UniProt Related Accession: | Q9UKS7 |
| Molecular Weight: | 60kDa |
| NCBI Full Name: | Zinc finger protein Helios |
| NCBI Synonym Full Names: | IKAROS family zinc finger 2 |
| NCBI Official Symbol: | IKZF2 |
| NCBI Official Synonym Symbols: | ANF1A2; HELIOS; ZNF1A2; ZNFN1A2 |
| NCBI Protein Information: | zinc finger protein Helios |
| UniProt Protein Name: | Zinc finger protein Helios |
| UniProt Synonym Protein Names: | Ikaros family zinc finger protein 2 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | IKZF2 |
