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Cell Biology Antibodies 14 Anti-K63-linkage Specific Polyubiquitin Antibody CAB18164
Key Features

K63-linkage Specific Polyubiquitin Rabbit Polyclonal Antibody (CAB18164)

Datasheet MSDS
SKU CAB18164
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse, Rat, Other (Wide Range Predicted)
Host Species Rabbit
Research Use Cell Biology
$149 - $603

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Description

system_update_altDatasheetsystem_update_altMSDS

K63-linkage Specific Polyubiquitin Antibody (CAB18164)

The K63-linkage Specific Polyubiquitin Antibody (CAB18164) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, specifically recognizes the K63-linked polyubiquitin chains and is highly reactive with human samples. Validated for use in Western blot applications, this antibody enables the detection and analysis of K63-linked polyubiquitin chains in various cell types.K63-linked polyubiquitin chains play a critical role in diverse cellular processes, including DNA repair, protein degradation, and immune responses.

This antibody is validated for use in ELISA, DB applications and has demonstrated reactivity against Human, Mouse, Rat, Other (Wide Range Predicted) samples.

Product Name:K63-linkage Specific Polyubiquitin Antibody
SKU:CAB18164
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat, Other (Wide Range Predicted)
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Tested Applications:ELISA DB
Recommended Dilution:
DB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Positive Sample:HeLa, HeLa+MG132, NIH/3T3, C6, Mouse brain, Rat brain
Observed MW:15-200kDa

Ubiquitination,onetypeofthemostcommonpost-translationalmodification,mediatestheregulationofproteinhomeostasisinvivo.SinceubiquitinitselfcontainsmultiplelysineresiduesandoneN-terminalfreeaminogroup,eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development （PMID: 19217402，PMCID: PMC3008764）.

Purification MethodAffinity purification
RRIDAB_2861949
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageDot-blot analysis of all sorts of peptides using K63-linkage Specific Polyubiquitin antibody (CAB18164) at 1:1000 dilution.
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