[KD Validated] COX7A2L Polyclonal Antibody
- SKU:
- CAB23681
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | [KD Validated] COX7A2L Polyclonal Antibody |
| Product Code: | CAB23681 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Mitochondrion inner membrane |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
| Immunogen: | Recombinant protein of human COX7A2L. |
| Sequence: | MYYKF SGFTQ KLAGA WASEA YSPQG LKPVV STEAP PIIFA TPTKL TSDST VYDYA GKNKV PELQK FFQKA DGVPV YLKRG LPDQM LYRTT MALTV GGTIY CLIAL YMASQ PKNK |
| Synonyms: | EB1, SCAF1, SCAFI, SIG81, COX7AR, COX7RP |
| Calculated MW: | 13kDa |
| Observed MW: | 14kDa |
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