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Anti-KDM4B / JMJD2B Antibody (CAB6670)

SKU:
CAB6670
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-KDM4B / JMJD2B Antibody
Antibody SKU:CAB6670
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human KDM4B / JMJD2B
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HCT116, Mouse brain
Immunogen:A synthesized peptide derived from human KDM4B / JMJD2B
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:23030
Uniprot:O94953
Cellular Location:
Calculated MW:150kDa
Observed MW:150KDa
Synonyms:JMJD2B, TDRD14B
Background:
UniProt Protein Function:JMJD2B: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Belongs to the JHDM3 histone demethylase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 1.14.11.-; Oxidoreductase; Demethylase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function:histone demethylase activity

UniProt Code:O94953
NCBI GenInfo Identifier:134047803
NCBI Gene ID:23030
NCBI Accession:O94953.4
UniProt Secondary Accession:O94953,O75274, Q6P3R5, Q9P1V1, Q9UF40, B9EGN8, D6W631
UniProt Related Accession:O94953
Molecular Weight:50,582 Da
NCBI Full Name:Lysine-specific demethylase 4B
NCBI Synonym Full Names:lysine demethylase 4B
NCBI Official Symbol:KDM4B  
NCBI Official Synonym Symbols:JMJD2B; TDRD14B  
NCBI Protein Information:lysine-specific demethylase 4B
UniProt Protein Name:Lysine-specific demethylase 4B
UniProt Synonym Protein Names:JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
Protein Family:Lysine-specific demethylase
UniProt Gene Name:KDM4B  
UniProt Entry Name:KDM4B_HUMAN
Anti-KDM4B / JMJD2B Antibody (CAB6670)Western blot - KDM4B / JMJD2B Rabbit mAb (CAB6670)

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